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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T2306 | Brexpiprazole | OPC-34712 | Dopamine Receptor , 5-HT Receptor , Adrenergic Receptor |
Brexpiprazole (OPC-34712) is a partial agonist of human 5-hydroxytryptamine (5-HT) 5-HT1A and dopamine D2 receptors. | |||
T8690 | Brexpiprazole HCl | OPC 34712 dihydrochloride | Others |
Brexpiprazole HCl (OPC 34712 dihydrochloride) is a new antipsychotic drug. | |||
T81335 | PZ-1922 | 5-HT Receptor | |
PZ-1922 (Compound 16), able to cross the blood-brain barrier, is a dual antagonist for 5-HT6R and 5-HT3R with K i values of 17 nM and 0.45 nM, respectively. It also reversibly inhibits MAO-B with a pIC50 of 8.93. Moreove... | |||
T83825 | Trofinetide acetate | NNZ-2566 | |
Trofinetide, derived from the neuroprotective tripeptide Gly-Pro-Glu (an N-terminal sequence of insulin-like growth factor-1, IGF-1), shows promise in various neuroprotective models. At a concentration of 10 nM, it mitig... |